Research

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Using the process of Membrane Lipid Replacement (MLR) the Vibrant & Clear Wafer formula is intended to reverse the damage done to our cells and mitochondria by oxidative stress. Pivotal studies have been conducted at UCLA, Henry Ford Hospital, The Institute for Molecular Medicine and others.

Commercial phospholipids were first prepared in Germany in the 1920s, and quickly became one of the earliest “health foods”. Chemically, the term “phospholipid” relates to the fact that these molecules contain phosphorus. Hundreds of different phospholipids exist, but currently the nutraceutical phospholipids all come from one class: the glycerophospholipids. The Vibrant & Clear Wafer formula is a unique combination that allows the healthy phospholipids to stay intact during transport through the body.

Future

Besides the positive effects of phospholipids for cognition and energy shown on this website there is clinical and anecdotal evidence supporting health benefits of phospholipid supplementation which may have a much broader application. There is strong evidence that phospholipid supplementation may have a positive effect on SAD, Alzheimer’s, senile dementia, ADHD, fibromyalgia, sarcoidosis, arthritis, neuropathy, wound healing and other chronic debilitating factors although only limited clinical trials have been conducted. As an added bonus, phosphatidylcholine has been shown to help with the intestinal absorption of supplemental carotenoids.

Positive clinical studies on the phospholipids found in Vibrant & Clear Wafers are listed below. They are categorized by function. To read each study a link will open a new window in your browser and link you to the publishing website. These links will forward to US National Library of Medicine National Institutes of Health, Cambridge Journals, Journal of the International Society of Sports Nutrition and several others. Although there have been many positive studies done on Bovine Cortex PS we have excluded them from the list. We do not use Bovine Cortex PS in our wafers because of concerns due to Mad Cow disease.

Chronic Fatigue Syndrome Studies (CFS)

Clinical_Uses_MLR-NicolsonDiscoveries2016 Click Here
Metabolic features CFS-NaviauxPNAS2016 Click Here

Research Links by Function
Athletic-(PA) - muscle
Phosphatidic acid supplementation increases skeletal muscle hypertrophy and strength
http://www.jissn.com/content/10/S1/P13

Athletic-(PS) - stress
The effects of phosphatidylserine on endocrine response to moderate intensity exercise
http://www.jissn.com/content/5/1/11

Athletic-(PA) - muscle
Soy-derived Phosphatidic Acid, Lysophosphatidic acid and Phosphatidylserine are sufficient to induce an increase in mTOR signaling
http://www.jissn.com/content/10/S1/P7

Athletic-(PA) - muscle
Efficacy of phosphatidic acid ingestion on lean body mass, muscle thickness and strength gains in resistance-trained men
http://www.jissn.com/content/9/1/47

Athletic-(PS) - stress and cognition
The effects of IQPLUS Focus on cognitive function, mood and endocrine response before and following acute exercise
http://www.jissn.com/content/8/1/16

Athletic-(PS) - stress
The effects of phosphatidylserine on endocrine response to moderate intensity exercise
http://www.jissn.com/content/5/1/11

Athletic-(PS) - golf
The effect of phosphatidylserine on golf performance
http://www.jissn.com/content/4/1/23

Athletic-(PS, PC) – cycling, weightlifting, running, athletics stress, recovery
Phospholipids and sports performance
http://www.jissn.com/content/4/1/5

Athletic-(PS) - stress and cognition
The effects of phosphatidylserine supplementation on cognitive functioning prior and following an acute bout of resistance training in young males
http://www.jissn.com/content/7/S1/P2

Athletic-(PS) - cycling
Effects of phosphatidylserine on exercise capacity during cycling in active males. http://www.ncbi.nlm.nih.gov/pubmed/16394955   

Cognition-(PS) – memory
Soybean-derived phosphatidylserine improves memory function of the elderly Japanese subjects with memory complaints.
http://www.ncbi.nlm.nih.gov/pubmed/21103034

Cognition-(PS) – memory
Phosphatidylserine containing omega-3 fatty acids may improve memory abilities in non-demented elderly with memory complaints: a double-blind placebo-controlled trial.
http://www.ncbi.nlm.nih.gov/pubmed/20523044

Cognition-(PS) – memory
Safety of soy-derived phosphatidylserine in elderly people.
http://www.ncbi.nlm.nih.gov/pubmed/12385596

Cognition-(PS) – memory
The effect of soybean-derived phosphatidylserine on cognitive performance in elderly with subjective memory complaints: a pilot study.
http://www.ncbi.nlm.nih.gov/pubmed/23723695

Cognition-(PS) – memory
An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline.
http://www.ncbi.nlm.nih.gov/pubmed/11201936?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Cognition-(PS, PE) – memory
Fatty acid composition of brain phospholipids in aging and in Alzheimer's disease.
http://www.ncbi.nlm.nih.gov/pubmed/1881238?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Cognition - ADHD - (PS) – children, symptoms
The effect of phosphatidylserine containing Omega3 fatty-acids on attention-deficit hyperactivity disorder symptoms in children: a double-blind placebo-controlled trial, followed by an open-label extension.
http://www.ncbi.nlm.nih.gov/pubmed/21807480

Cognition - ADHD - (PS) – children, symptoms
The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial.
http://www.ncbi.nlm.nih.gov/pubmed/23495677

Cognition-(PS, PE) – memory
Learning behaviour and cerebral protein kinase C, antioxidant status, lipid composition in senescence-accelerated mouse: influence of a phosphatidylcholine–vitamin B12 diet
http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=892284

Energy – (PS)
Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179068/

Energy – (PC, PE, PG, PI, PS)
Lipid Replacement Therapy: A natural medicine approach to replacing damaged lipids in cellular membranes and organelles and restoring function.
http://www.ncbi.nlm.nih.gov/pubmed/24269541

Energy – (All Lipids)
Metabolic syndrome and mitochondrial function: molecular replacement and antioxidant supplements to prevent membrane peroxidation and restore mitochondrial function.
http://www.ncbi.nlm.nih.gov/pubmed/17243117

Mood – (PS)
The influence of phosphatidylserine supplementation on mood and heart rate when faced with an acute stressor.
http://www.ncbi.nlm.nih.gov/pubmed/11842886

Mood – (PS, PA)
Effects of soy lecithin phosphatidic acid and phosphatidylserine complex (PAS) on the endocrine and psychological responses to mental stress.
http://www.ncbi.nlm.nih.gov/pubmed/15512856 

Overall Health – (All Lipids)
Lipid analogues as potential drugs for the regulation of mitochondrial cell death.
http://www.ncbi.nlm.nih.gov/pubmed/24111728

Overall Health – (All Lipids)
Mitochondrial Dysfunction and Chronic Disease: Treatment With Natural Supplements.
http://www.ncbi.nlm.nih.gov/pubmed/24002683

Overall Health – (All Lipids) - Cholesterol
Egg consumption modulates HDL lipid composition and increases the cholesterol-accepting capacity of serum in metabolic syndrome.
http://www.ncbi.nlm.nih.gov/pubmed/23494579

 

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any pharmaceutical product without first consulting your prescribing physician. Resale of Vibrant & Clear Wafers without written permission is strictly prohibited.